We are in relentless pursuit of breakthroughs that change patients' lives. We innovate every day to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Studies show what intuition tells us: that purpose-driven companies perform better, are more innovative, draw and keep the best people, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and embodies the value we aim to bring to patients and society. Our purpose guarantees that patients remain at the core of all we do. We live our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.