We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation each day to make the world a healthier place. It was Charles Pfizer's original vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies deliver better results, are more creative, draw and keep the best people, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and reflects our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we work to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We live our purpose by finding the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.