We're in constant pursuit of breakthroughs that improve patients' lives. We drive innovation each day to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best people, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and reflects the value we work to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We fulfill our purpose by seeking the best science in the world, partnering with others in the healthcare system to increase access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.