We are in tireless pursuit of breakthroughs that change patients' lives. We create innovations each day to make the world a better place. This was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more creative, recruit and maintain the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and demonstrates our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We live our purpose by sourcing the best science in the world, working with others in the healthcare system to increase access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.