We are in tireless pursuit of breakthroughs that improve patients' lives. We innovate daily to make the world a more healthy place. It was Charles Pfizer's original vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best people, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and reflects the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.