We are in relentless pursuit of breakthroughs that change patients' lives. We create innovations every day to make the world a better place. This was Charles Pfizer's founding vision, and it holds true today. Studies show what we instinctively know: that purpose-driven companies achieve more, are more inventive, draw and keep the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we strive to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.