We are in tireless pursuit of breakthroughs that transform patients' lives. We drive innovation every day to make the world a better place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what we instinctively know: that purpose-driven companies deliver better results, are more creative, attract and retain the best talent, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has meaning and represents the value we work to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We live our purpose by seeking the best science in the world, partnering with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.