We're in constant pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a better place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, recruit and maintain the best professionals, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and demonstrates our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we work to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.