We're in constant pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a better place. This was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, draw and keep the best professionals, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We fulfill our purpose by finding the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.